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Rimonabant, brand named Acomplia, is an anti-obesity drug that may help treat addiction, the team noted. Food and Drug Administration finding of increased risk of suicide during treatment with rimonabant, we recommend increased alertness by physicians to these potentially severe psychiatric adverse reactions. 15 -- People who take the weight-loss drug rimonabant may face heightened risks for severe depression and anxiety, Danish researchers report. 16 issue of the British Medical Journal, Padwal's team found that long-term users of weight-loss drugs such as orlistat (Xenical), sibutramine (Meridia) and rimonabant experienced only modest weight loss -- less than 11 pounds, which was less than 5 percent of their total body weight. A CB1 antagonist called rimonabant is currently marketed overseas for weight loss. Effect of Rimonabant on Body Weight and the Metabolic Syndrome in Overweight Patients.

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